Michell A R
Q J Exp Physiol Cogn Med Sci. 1980 Jan;65(1):27-36. doi: 10.1113/expphysiol.1980.sp002489.
Previous studies of voluntary sodium intake and electrolyte excretion in sheep suggested that the pattern of intake associated with the oestrous cycle was not a response to alterations in sodium balance. The pattern thus seemed likely to be dictated by changes in either hormonal levels or food intake. These possibilities were examined in experiments with ovariectomized sheep. Physiological doses of oestrogen or progesterone had no effect on sodium preference, whether given in isolation or succession. Depression of food intake by 25% (as at oestrus) did affect preference slightly (though significantly) but in the opposite direction to the change at oestrus. It is concluded that none of these 3 factors is responsible for the varying sodium preference during the oestrous cycle and that direct hypothalamic control of this pattern is an interesting possibility.
先前对绵羊自愿钠摄入量和电解质排泄的研究表明，与发情周期相关的摄入模式并非对钠平衡变化的反应。因此，这种模式似乎可能由激素水平或食物摄入量的变化所决定。在对去卵巢绵羊进行的实验中对这些可能性进行了研究。生理剂量的雌激素或孕酮，无论是单独给予还是相继给予，对钠偏好均无影响。食物摄入量降低25%（如在发情期时）确实对偏好有轻微（尽管显著）影响，但方向与发情期的变化相反。得出的结论是，这三个因素均与发情周期中钠偏好的变化无关，下丘脑对这种模式的直接控制是一种有趣的可能性。
