Calcifying epithelial odontogenic tumor: histochemical properties of homogeneous acellular substances in the tumor.

Calcifying epithelial odontogenic tumor (CEOT) is characterized by the presence of homogeneous, acellular, eosinophilic, and calcifying substances. The histochemical properties of homogeneous acellular substances are compared to enamel matrix in the human developing teeth. Homogeneous amorphous material in the CEOT is not amyloid histochemically; the composition of materials are compared to the proteins of enamel matrix. The findings of CEOT from the Japanese literature are introduced clinically and radiographically.