氯化铵对绵羊肝血流量的抑制作用。

The depressive action of ammonium chloride on the hepatic blood flow in sheep.

作者信息

Barej W, Siwecka B, Gronczewski J, Skolasinska K

出版信息

Q J Exp Physiol Cogn Med Sci. 1980 Apr;65(2):99-104. doi: 10.1113/expphysiol.1980.sp002503.

DOI:10.1113/expphysiol.1980.sp002503

Abstract

Using the 133Xe clearance method it is shown that NH4Cl infusion into the anterior mesenteric vein decreased capillary blood flow in the liver. Phentolamine completely and propranolol partially prevented the depressive action of NH4Cl on hepatic blood flow. NH5Cl infused into the jugular vein provoked a slight increase in the hepatic blood flow. The adrenaline-like action of ammonium ion on the blood circulation in the liver region is discussed.

摘要

采用¹³³Xe清除法研究发现，向肠系膜前静脉输注氯化铵会降低肝脏的毛细血管血流量。酚妥拉明可完全消除、普萘洛尔可部分消除氯化铵对肝血流量的抑制作用。向颈静脉输注氯化铵会使肝血流量略有增加。文中讨论了铵离子对肝脏区域血液循环的类肾上腺素作用。