Chaiyabuter N, Faulkner A, Peaker M
Q J Exp Physiol Cogn Med Sci. 1980 Jul;65(3):207-16. doi: 10.1113/expphysiol.1980.sp002507.
In conscious goats, starved for 48 hr, in mid-pregnancy (70 days) cardiac output and blood volume decreased; total peripheral resistance increased; heart rate, stroke volume, blood pressure, mammary blood flow and mammary resistance were not significantly affected. In late pregnancy (132 days) cardiac output, heart rate, blood volume and mammary blood flow fell; peripheral resistance increased; stroke volume and blood pressure were not significantly affected. In mid-pregnancy, water consumption fell and the animal entered a stage of negative sensible water balance which persisted for both days of starvation. A similar change was obtained on the first day in late-pregnant goats, but on the second day water consumption increased and positive water balance was restored. Cardiac output, heart rate, blood volume and mammary blood flow was higher in fed late-pregnant than in fed mid-pregnant goats, total peripheral resistance was lower while there were no significant changes in stroke volume or blood pressure. Indications of correlations between litter size and cardiac function were obtained. The results are compared with previous studies on the effects of starvation in lactating animals and are discussed in relation to the control of cardiac function and mammary blood flow in pregnancy and lactation.
在妊娠中期（70天）饥饿48小时的清醒山羊中，心输出量和血容量下降；总外周阻力增加；心率、每搏输出量、血压、乳腺血流量和乳腺阻力未受到显著影响。在妊娠后期（132天），心输出量、心率、血容量和乳腺血流量下降；外周阻力增加；每搏输出量和血压未受到显著影响。在妊娠中期，饮水量下降，动物进入负水平衡阶段，该阶段在饥饿的两天内持续存在。在妊娠后期的山羊中，第一天出现了类似的变化，但第二天饮水量增加，恢复了正水平衡。妊娠后期进食的山羊的心输出量、心率、血容量和乳腺血流量高于妊娠中期进食的山羊，总外周阻力较低，而每搏输出量或血压没有显著变化。获得了产仔数与心功能之间相关性的指标。将结果与先前关于饥饿对泌乳动物影响的研究进行了比较，并就妊娠和泌乳期间心功能和乳腺血流量的控制进行了讨论。
