乙酰水杨酸预处理对再形成房水的影响。一项关于人眼囊内晶状体摘除术的研究。

The effect of acetyl-salicylic-acid pretreatment on re-formed aqueous humor. A study of intracapsular lens extraction in the human eye.

作者信息

Grabner G, Dorda W, Zehetbauer G, Bettelheim H, Hruby K

出版信息

Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1980;214(1):61-7. doi: 10.1007/BF00414538.

Abstract

Aqueous humor (a.h.) was sampled in 67 patients operated on for cataract by intracapsular lens extraction at the start and finish of surgery. Twenty eight of these patients received pretreatment with acetyl-salicylic acid (ASA), to a total of 2.5 g, beginning 18 hours prior to surgery. A serum sample was drawn immediately following the operation from 55 patients. Using radial immunodiffusion, albumin and IgG were measured in primary and secondary a.h. and in serum. The group pretreated with ASA showed a significantly smaller relative increase of IgG (P < 0.05). The increase of the proteins, however, showed no dependence on their serum-level and the only side-effect of the treatment was an unexplained rise in serum-albumin. The possible clinical application of patients with a high risk of postoperative complications is briefly summarized.

摘要

对67例行白内障囊内晶状体摘除术的患者，在手术开始时和结束时采集房水样本。其中28例患者在手术前18小时开始接受乙酰水杨酸（ASA）预处理，总量为2.5g。术后立即从55例患者中采集血清样本。采用放射免疫扩散法，检测原发性和继发性房水以及血清中的白蛋白和IgG。接受ASA预处理的组中，IgG的相对增加明显较小（P<0.05）。然而，蛋白质的增加与它们的血清水平无关，该治疗的唯一副作用是血清白蛋白出现无法解释的升高。简要总结了术后并发症高风险患者的可能临床应用。