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母亲接受抗生素治疗对新生儿肠道杆菌科细菌定植的影响(作者译)

[Effect of antibiotic therapy in the mother on the colonization of the newborn by enterobacteriaceae (author's transl)].

作者信息

Borderon J C, Bernard J C, Vergnaud R, Gold F, Soutoul J H, Laugier J

出版信息

Arch Fr Pediatr. 1980 Jun;37(6):371-6.

PMID:6903438
Abstract

Two studies were undertaken to determine the effect of antibiotic therapy in the mother on the enterobacteriaceae of the newborn's fecal flora. In the first, mothers were given tetracycline after delivery. Although the effect on the maternal flora was important there was no noticeable effect on the enterobacteriaceae of the newborn although the organisms were predominantly susceptible. In the second, mothers were given ampicillin before delivery and resistant enterobacteriaceae were predominant in all the newborns. In the controls born to untreated mothers susceptible organism still predominate. Antibiotic treatment of the mother has an important effect on the newborn's flora if the treatment is given before delivery.

摘要

进行了两项研究以确定母亲接受抗生素治疗对新生儿粪便菌群中肠杆菌科细菌的影响。在第一项研究中,母亲在分娩后服用四环素。尽管对母体菌群的影响很大,但对新生儿的肠杆菌科细菌没有明显影响,尽管这些微生物大多是敏感的。在第二项研究中,母亲在分娩前服用氨苄青霉素,所有新生儿中耐药肠杆菌科细菌占主导。在未接受治疗的母亲所生的对照组中,敏感菌仍然占主导。如果在分娩前进行治疗,母亲的抗生素治疗对新生儿的菌群有重要影响。

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