Kissling W, Emrich H M, Fischler M, von Zerssen D, Riedhammer H, Edel H H
Fortschr Neurol Psychiatr Grenzgeb. 1980 Jul;48(7):393-400. doi: 10.1055/s-2007-1002392.
In an open study three chronically schizophrenic patients with normal kidney function were treated by hemodialysis in an attempt to ameliorate their psychotic symptoms. Neuroleptic treatment was stopped at least four weeks prior to hemodialysis. The patients were dialysed once weekly for twelve (in one case eleven) weeks. Psychopathology was evaluated using the IMPS, BPRS and NOSIE. No patient showed any improvement during the course of dialysis, one patient showed a marked detrioration. These observations raise doubts about whether schizophrenic psychoses can be improved by means of hemodialysis as previously published by Wagemaker (1977).
在一项开放性研究中，对三名肾功能正常的慢性精神分裂症患者进行了血液透析治疗，试图改善他们的精神病症状。在血液透析前至少四周停止使用抗精神病药物治疗。患者每周透析一次，持续十二周（其中一例为十一周）。使用IMPS、BPRS和NOSIE对精神病理学进行评估。在透析过程中，没有患者表现出任何改善，一名患者病情明显恶化。这些观察结果使人怀疑，如Wagemaker（1977年）之前发表的那样，精神分裂症精神病是否能通过血液透析得到改善。
