Meurice E
Acta Psychiatr Belg. 1986 May-Jun;86(3):266-86.
A review is made of 325 published cases of schizophrenic patients who underwent series of hemodialysis. In 211 cases the series of dialysis were open studies; 49 of these patients (23%) were markedly improved. In 114 other patients the effects of actual and sham dialysis were compared in a double blind experiment. A marked improvement was found in 24 cases (21%). But results of sham and actual hemodialysis did not differ significantly. Hemopurification is therefore not the cause of improvement. The rate of marked improvement is however clearly higher than what one could expect in chronic schizophrenics from a simple placebo effect. The various possible causes for this special effect are discussed. It is proposed that about 20% of schizophrenic patients could favorably react to the strong healing involvement of the psychiatrist, especially when a magic aspect is implied. This should encourage to approach patients not responding to conventional therapy with more optimism and possibly with new methods.
对325例接受系列血液透析的精神分裂症患者的已发表病例进行了回顾。在211例病例中，透析系列为开放性研究；其中49例患者（23%）有显著改善。在另外114例患者中，在双盲实验中比较了实际透析和假透析的效果。24例（21%）有显著改善。但假透析和实际血液透析的结果没有显著差异。因此，血液净化不是改善的原因。然而，显著改善的比例明显高于慢性精神分裂症患者单纯安慰剂效应所能预期的比例。讨论了这种特殊效应的各种可能原因。有人提出，约20%的精神分裂症患者可能会对精神科医生强烈的治疗参与产生良好反应，尤其是当涉及到神奇的方面时。这应该鼓励以更乐观的态度并可能采用新方法来治疗对传统疗法无反应的患者。
