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Male mouse submaxillary gland secretes highly toxic proteins.

作者信息

Hiramatsu M, Hatakeyama K, Minami N

出版信息

Experientia. 1980 Aug 15;36(8):940-2. doi: 10.1007/BF01953804.

DOI:10.1007/BF01953804
PMID:6904301
Abstract

Submaxillary gland saliva induced by phenylephrine from male mice was highly toxic to guinea-pigs, rats and hamsters, whereas the toxicity was relatively low to mice. One of the toxic components in the saliva was isolated as a kallikrein-like enzyme.

摘要

相似文献

1
Male mouse submaxillary gland secretes highly toxic proteins.
Experientia. 1980 Aug 15;36(8):940-2. doi: 10.1007/BF01953804.
2
Lethal factor in the male mouse submandibular gland.
Can J Physiol Pharmacol. 1981 Nov;59(11):1134-8. doi: 10.1139/y81-175.
3
[Studies on the lethal factor in the mouse submandibular gland].
Josai Shika Daigaku Kiyo. 1984;13(1):44-59.
4
Aggression-provoked huge release of submaxillary mouse renin to saliva.攻击引发小鼠颌下腺肾素大量释放至唾液中。
Acta Endocrinol (Copenh). 1983 Dec;104(4):510-2. doi: 10.1530/acta.0.1040510.
5
The release of glandular kallikrein from submaxillary glands of rats exposed to heat.受热大鼠颌下腺中腺激肽释放酶的释放。
Arch Int Physiol Biochim Biophys. 1994 May-Jun;102(3):183-8. doi: 10.3109/13813459409007535.
6
Intracellular distribution of submaxillary kallikrein.颌下腺激肽释放酶的细胞内分布
J Physiol. 1968 May;196(2):431-45. doi: 10.1113/jphysiol.1968.sp008516.
7
Rat submandibular gland kallikreins: purification and cellular localization.
Br J Pharmacol. 1976 Feb;56(2):155-67. doi: 10.1111/j.1476-5381.1976.tb07438.x.
8
Kallikrein, trypsin-like proteases and amylase in mammalian submaxillary glands.哺乳动物颌下腺中的激肽释放酶、类胰蛋白酶和淀粉酶。
Br J Pharmacol. 1971 Dec;43(4):784-93. doi: 10.1111/j.1476-5381.1971.tb07214.x.
9
Stimulus-secretion coupling: role of cyclic AMP, cyclic GMP and calcium in mediating enzyme (kallikrein) secretion in the submandibular gland.刺激-分泌偶联:环磷酸腺苷、环磷酸鸟苷和钙在介导下颌下腺中酶(激肽释放酶)分泌中的作用。
J Physiol. 1976 Jul;258(3):631-58. doi: 10.1113/jphysiol.1976.sp011438.
10
The regulation of kallikrein secretion from isolated submandibular gland slices by neurotransmitters, cyclic nucleotides and calcium.神经递质、环核苷酸和钙对分离的下颌下腺切片激肽释放酶分泌的调节
Adv Exp Med Biol. 1976;70(00):59-64. doi: 10.1007/978-1-4684-3267-1_8.

引用本文的文献

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Co-option of the same ancestral gene family gave rise to mammalian and reptilian toxins.相同的祖先基因家族的趋同进化产生了哺乳动物和爬行动物毒素。
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An ancient, conserved gene regulatory network led to the rise of oral venom systems.一个古老而保守的基因调控网络导致了口腔毒液系统的出现。
Proc Natl Acad Sci U S A. 2021 Apr 6;118(14). doi: 10.1073/pnas.2021311118.
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How the Toxin got its Toxicity.毒素如何获得其毒性。

本文引用的文献

1
A simplified method of evaluating dose-effect experiments.一种评估剂量效应实验的简化方法。
J Pharmacol Exp Ther. 1949 Jun;96(2):99-113.
2
PURIFICATION OF A NERVE-GROWTH PROMOTING PROTEIN FROM THE MOUSE SALIVARY GLAND AND ITS NEURO-CYTOTOXIC ANTISERUM.从小鼠唾液腺中纯化一种神经生长促进蛋白及其神经细胞毒性抗血清。
Proc Natl Acad Sci U S A. 1960 Mar;46(3):302-11. doi: 10.1073/pnas.46.3.302.
3
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
Front Pharmacol. 2020 Dec 14;11:574925. doi: 10.3389/fphar.2020.574925. eCollection 2020.
J Biol Chem. 1951 Nov;193(1):265-75.
4
DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.圆盘电泳。II. 方法及其在人血清蛋白中的应用。
Ann N Y Acad Sci. 1964 Dec 28;121:404-27. doi: 10.1111/j.1749-6632.1964.tb14213.x.
5
[Isolation and structure of kallidine].[缓激肽释放酶原的分离与结构]
Hoppe Seylers Z Physiol Chem. 1961 Nov 24;326:174-6. doi: 10.1515/bchm2.1961.326.1.174.
6
Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal.从小鼠颌下腺中分离出一种可加速新生动物门齿萌出和睁眼的蛋白质。
J Biol Chem. 1962 May;237:1555-62.
7
Effect of testosterone and duct ligation on submaxillary renin-like principle.睾酮与输精管结扎对颌下腺肾素样物质的影响。
Am J Physiol. 1967 Aug;213(2):341-6. doi: 10.1152/ajplegacy.1967.213.2.341.
8
Testosterone induction of estero-proteolytic activity in the mouse submaxillary gland.睾酮诱导小鼠颌下腺酯解活性的研究
Biochim Biophys Acta. 1967 Jul 11;139(2):372-81. doi: 10.1016/0005-2744(67)90041-1.
9
Isoelectric fractionation, analysis, and characterization of ampholytes in natural pH gradients. IV. Further studies on the resolving power in connection with separation of myoglobins.天然pH梯度中两性电解质的等电分级分离、分析及特性鉴定。IV. 与肌红蛋白分离相关的分辨率的进一步研究。
Acta Chem Scand. 1966;20(3):820-34. doi: 10.3891/acta.chem.scand.20-0820.
10
Ultrastructure of mouse submaxillary gland. I. Sexual differences.小鼠颌下腺的超微结构。I. 性别差异。
J Ultrastruct Res. 1966 Dec;16(5):505-23. doi: 10.1016/s0022-5320(66)80003-5.