De Grandis D, Fiaschi A, Tomelleri G, Orrico D
J Neurol Sci. 1978 Jun;37(1-2):107-12. doi: 10.1016/0022-510x(78)90231-9.
The neurophysiological findings obtained with standard electromyography (EMG) and single fiber EMG (SFEMG) in a case of hypokalemic periodic paralysis (HoPP) are reported. During the period between paralytic attacks the only abnormalities consisted of scanty fibrillation potentials and, with SFEMG, a fiber density increase. In the first stage of an induced paralytic attack the most striking feature was decrease in fiber density, slight increase in jitter with several blocks. These results indicate a failure of the membrane surface to propagate an action potential. In some fibers the block is likely to be permanent, thus explaining the decrease in fiber density. The jitter increase is due to a slight abnormality at the synaptic site or to a variation in the propagation velocity of the muscle fiber.
报告了在一例低钾性周期性麻痹（HoPP）患者中使用标准肌电图（EMG）和单纤维肌电图（SFEMG）获得的神经生理学发现。在麻痹发作期间，唯一的异常包括少量纤颤电位，以及使用SFEMG时纤维密度增加。在诱发性麻痹发作的第一阶段，最显著的特征是纤维密度降低、微增和数处阻滞。这些结果表明膜表面传播动作电位失败。在一些纤维中，阻滞可能是永久性的，从而解释了纤维密度的降低。微增是由于突触部位的轻微异常或肌纤维传播速度的变化。
