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睾酮在实验性酒精中毒发展中的作用。

The role of testosterone in the development of experimental alcoholism.

作者信息

Lakoza G N, Barkov N K

出版信息

Bull Narc. 1980;32(2):41-8.

PMID:6907025
Abstract

The hormonal effects of testosterone, progesterone and extradiol on voluntary preference of ethanol were investigated in experiments carried out on castrated male albino rats. It was observed that testosterone stimulated the development of ethanol preference, while the effects of progesterone and estradiol were significantly slower and less intensive. It was also observed that the androgenic action of testosterone was more important than its anabolic action in stimulating ethanol preference.

摘要

在对去势雄性白化大鼠进行的实验中,研究了睾酮、孕酮和雌二醇对乙醇自愿偏好的激素作用。观察到睾酮刺激了乙醇偏好的发展,而孕酮和雌二醇的作用明显更慢且强度更低。还观察到,在刺激乙醇偏好方面,睾酮的雄激素作用比其合成代谢作用更重要。

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