大颗粒聚合白蛋白中锝-99m制剂中总游离锝-99m的快速检测：简报
Rapid assay for total unbound Tc-99m in preparations of Tc-99m in macroaggregated albumin: concise communication.
作者信息
McLean J R
出版信息
J Nucl Med. 1978 Sep;19(9):1045-8.
PMID:690705
Abstract
A rapid economic filter-paper assay for determining total unbound Tc-99m in preparations of Tc-99m macroaggregated albumin (Tc-99m MAA) is described. The procedure uses Whatman 542 filter-papter discs and aqueous 0.009% NaCl as wash solution. The principal radiochemical impurities found in Tc-99m MAA kits are not significantly adsorbed to the filter matrix. The procedure can be completed in 1--2 min and gives results comparable to those obtained by the centrifuge assay (USP XIX).
摘要
本文描述了一种用于测定锝-99m 大颗粒白蛋白（Tc-99m MAA）制剂中总未结合锝-99m 的快速经济的滤纸分析法。该方法使用沃特曼542滤纸圆盘和0.009%的氯化钠水溶液作为洗涤溶液。在Tc-99m MAA试剂盒中发现的主要放射化学杂质不会显著吸附到滤纸基质上。该方法可在1-2分钟内完成，其结果与通过离心分析法（美国药典第十九版）获得的结果相当。
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