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高血压流行病学作为治疗与控制的指南

Epidemiology of hypertension as a guide to treatment and control.

作者信息

Borhani N O

出版信息

Heart Lung. 1981 Mar-Apr;10(2):245-54.

PMID:6907259
Abstract

Knowledge of the epidemiology of hypertension can be used as an excellent guide in treatment and control of hypertension in the community. Available evidence on the epidemiology of hypertension that has direct bearing on clinical decisions for diagnosis and treatment can be listed as follows: 1. Frequently distribution of arterial blood pressure in a population of unimodal and continuous. 2. The adverse effects of high blood pressure (e.g., death) are related numerically to the level of blood pressure, both systolic and diastolic. 3. Prevalence of actual hypertension in the community depends upon the variability of blood pressure between occasions of measurement, and the arbitrary cutoff points used in screening. 4. Prevalence rates of actual hypertension in the community are the same for men and women and differ by race; the rate is higher in black than in white subjects. 5. Although the proportion of those cases of hypertension under control has increased dramatically in the United States communities since 1974, a disparity exists between men and women in the degree of their hypertension control. More women (black and white) than men have their hypertension under control. 6. There is an interaction between blood pressure and other risk factors. Decision on treatment should be based on total health profiles of the patient and not just the level of blood pressure. 7. Results of recent experimental epidemiologic studies (HDFP) indicate that judicious and rigorous treatment of mild hypertension in the community is feasible and that such a treatment is successful in reducing total mortality rate in the community by at least 17%.

摘要

高血压流行病学知识可作为社区高血压治疗与控制的绝佳指导。与高血压诊断和治疗临床决策直接相关的现有高血压流行病学证据如下:1. 人群中动脉血压呈单峰连续分布。2. 高血压的不良影响(如死亡)在数值上与收缩压和舒张压水平相关。3. 社区中实际高血压的患病率取决于测量次数间血压的变异性以及筛查中使用的任意临界值。4. 社区中实际高血压的患病率在男性和女性中相同,但因种族而异;黑人的患病率高于白人。5. 尽管自1974年以来美国社区中得到控制的高血压病例比例大幅增加,但男性和女性在高血压控制程度上仍存在差异。得到控制的高血压女性(黑人和白人)比男性更多。6. 血压与其他危险因素之间存在相互作用。治疗决策应基于患者的整体健康状况,而不仅仅是血压水平。7. 近期实验性流行病学研究(高血压检测与随访计划)结果表明,在社区中明智且严格地治疗轻度高血压是可行的,且这种治疗成功将社区总死亡率至少降低了17%。

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