Townsend J C, Ott M G, Fishbeck W A
J Occup Med. 1978 Aug;20(8):543-8. doi: 10.1097/00043764-197808000-00006.
We previously conducted a cohort mortality study of 594 individuals occupationally exposed to measured concentrations of benzene. This report presents health examination findings for a subset of 282 men from the larger group. Although slight decreases in mean total bilirubin and RBC values were detected statistically in comparing the exposed group to controls, these changes were not regarded as clinically significant. No correlations were found between peripheral blood counts and latency, duration or intensity of benzene exposure. Presently we have no indication from our data of adverse effects of benzene having occurred in our subset. Variation in latency among individuals and the possibility of subtle changes effecting an eventual pattern contribute to the need for continued surveillance.
我们之前对594名职业性接触实测苯浓度的个体进行了队列死亡率研究。本报告呈现了来自该较大群体中282名男性子集的健康检查结果。尽管在将暴露组与对照组进行比较时，统计学上检测到平均总胆红素和红细胞值略有下降，但这些变化不被视为具有临床意义。在外周血细胞计数与苯暴露的潜伏期、持续时间或强度之间未发现相关性。目前，我们的数据没有表明在我们的子集中已经发生了苯的不良影响。个体间潜伏期的差异以及细微变化影响最终模式的可能性，使得持续监测成为必要。
