[Monitoring of post-operative prevention of thrombosis by low dosage heparin with the radioactive iodine fibrinogen test (author's transl)].

In a prospective study low dosage subcutaneous heparin was administered to 148 patients after major gynaecological operations. The preventive effect on deep vein thrombosis was monitored by the radioactive iodine fibrinogen test. In 10.1% (15) of the cases higher than normal activity of the radioiodine fibrinogen test was detected. Only 4 patients (2.7%) had clinical signs of deep vein thrombosis. Because of the early occurrence of silent signs of deep vein thrombosis in the radioactive iodine fibrinogen test the onset of the subcutaneous heparin prophylaxis of thrombosis was shifted from the post-operative period to the pre-operative administration.