Luft F C, Bloch R, Szwed J J, Grim C M, Grim C E
JAMA. 1978 Oct 27;240(18):1985-7.
We treated eight severely hypertensive, long-term hemodialysis patients who failed to respond to ultrafiltration or conventional medication with minoxidil rather than with bilateral nephrectomy. Control of blood pressure and relief of symptoms was achieved in all eight. In addition, three of the patients, who were all severely oliguric, recovered sufficient renal function to allow the discontinuation of dialysis. Two are presently doing well, while one died of causes unrelated to uremia or minoxidil therapy. We presently reserve bilateral nephrectomy for those hypertensive dialysis patients who are awaiting transplantation.
我们对8例严重高血压的长期血液透析患者进行了治疗，这些患者对超滤或传统药物治疗无效，我们用米诺地尔而非双侧肾切除术对其进行治疗。所有8例患者的血压均得到控制，症状也得到缓解。此外，3例患者均为严重少尿，其肾功能恢复到足以停止透析的程度。目前，2例患者情况良好，1例死于与尿毒症或米诺地尔治疗无关的原因。我们目前为那些等待移植的高血压透析患者保留双侧肾切除术。
