Dumas R, Baldet P, Rolin B, Jean R
Arch Dis Child. 1981 May;56(5):403-4. doi: 10.1136/adc.56.5.403.
An 11-year-old girl presented with acute renal failure and severe hypertension. The blood film showed thrombocytopenia, numerous fragmented red blood cells, and a reticulocyte count of 10%. An intravenous pyelogram showed a small contracted left kidney, and plasma renin activity was increased in the left renal vein. Treatment with minoxidil and propranolol controlled the hypertension. After nephrectomy the hypertension resolved. Light microscopical examination of the left kidney showed a segmental renal hypoplasia. Malignant arterial hypertension can provoke a syndrome of haemolysis and uraemia in children. Aggressive lowering of blood pressure leads to an improvement in renal function.
一名11岁女孩出现急性肾衰竭和严重高血压。血涂片显示血小板减少、大量破碎红细胞，网织红细胞计数为10%。静脉肾盂造影显示左肾小且萎缩，左肾静脉血浆肾素活性升高。用米诺地尔和普萘洛尔治疗控制了高血压。肾切除术后高血压得以缓解。左肾的光镜检查显示节段性肾发育不全。儿童恶性高血压可引发溶血和尿毒症综合征。积极降低血压可使肾功能改善。
