Rosenstein B J, Langbaum T S, Gordes E, Brusilow S W
JAMA. 1978 Oct 27;240(18):1987-8. doi: 10.1001/jama.240.18.1987.
The sweat test is the only practical and reliable laboratory test for confirmation of the diagnosis of cystic fibrosis. Among 234 patients referred to The Johns Hopkins Hospital for sweat testing, 62 had had a previous test; 29 tests had been reported as negative, and 33 tests had been reported as positive. Results of quantitative pilocarpine-iontophoresis sweat tests at this center led to a change in diagnosis in 27 (43.5%) of these 62 patients. Most of the errors were false-positive.
汗液测试是确诊囊性纤维化唯一实用且可靠的实验室检测方法。在转诊至约翰霍普金斯医院进行汗液测试的234名患者中，62人曾接受过此前的测试；29次测试报告为阴性，33次测试报告为阳性。该中心进行的毛果芸香碱离子电渗汗液定量测试结果使这62名患者中的27人（43.5%）诊断发生了改变。大多数错误为假阳性。
