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猫主动脉神经有髓和无髓纤维的终末及次级投射

The terminations and secondary projections of myelinated and non-myelinated fibres of the aortic nerve in the cat.

作者信息

Donoghue S, Fox R E, Kidd C, McWilliam P N

出版信息

Q J Exp Physiol. 1981 Oct;66(4):405-22. doi: 10.1113/expphysiol.1981.sp002583.

DOI:10.1113/expphysiol.1981.sp002583
PMID:6914677
Abstract

In anaesthetized cats the projection of myelinated and non-myelinated afferent fibres of the aortic nerve to the brain stem was studied by recording antidromic potentials evoked in the nerve by electrical stimulation of the medulla oblongata. Probable sites of termination of both myelinated and non-myelinated afferent fibres were found to be in the ipsilateral medial lateral subnucleus of the nucleus tractus solitarius, the ipsilateral area postrema, the commissural nucleus and the contralateral nucleus tractus solitarius about the level of the obex. No evidence for a projection of primary afferent fibres in the aortic nerve to the medial reticular formation was found. In a second series of experiments the aortic nerve was electrically stimulated and extracellular recordings were made from neurones in the medulla activated by afferent fibres in this nerve. Neurones activated by myelinated afferent fibres were located in the nucleus tractus solitarius, dorsal vagal motor nucleus, commissural nucleus, area postrema and lateral reticular formation including nucleus ambiguus. Neurones activated by non-myelinated afferent fibres were in or near the medial nucleus tractus solitarius, the area postrema, dorsal motor vagal nucleus and nucleus intercalatus. Few neurones appeared to be activated by both myelinated and non-myelinated afferent fibres and they were located in the medial nucleus tractus solitarius and nucleus ambiguus.

摘要

在麻醉猫中,通过电刺激延髓诱发主动脉神经中的逆向电位,研究了主动脉神经的有髓和无髓传入纤维向脑干的投射。发现有髓和无髓传入纤维的可能终止部位在同侧孤束核的内侧外侧亚核、同侧最后区、连合核以及延髓闩部水平的对侧孤束核。未发现主动脉神经中的初级传入纤维向内侧网状结构投射的证据。在第二组实验中,电刺激主动脉神经,并对由该神经传入纤维激活的延髓神经元进行细胞外记录。由有髓传入纤维激活的神经元位于孤束核、迷走背运动核、连合核、最后区和包括疑核在内的外侧网状结构。由无髓传入纤维激活的神经元位于孤束核内侧核或其附近、最后区、迷走背运动核和中间核。很少有神经元似乎被有髓和无髓传入纤维同时激活,它们位于孤束核内侧核和疑核。

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