Donoghue S, Fox R E, Kidd C, Koley B N
Q J Exp Physiol. 1981 Oct;66(4):391-404. doi: 10.1113/expphysiol.1981.sp002582.
In anaesthetized cats, right cardiac vagal branches were electrically stimulated and recordings of evoked 'slow wave' and single neurone activity were made in the brain stem. Short-latency 'slow wave' and multi-neuronal activity evoked by excitation of myelinated vagal afferent fibres were recorded in the medial and lateral subnuclei of the nucleus tractus solitarius, the area postrema, the dorsal vagal motor nucleus, the lateral reticular formation and the nucleus ambiguus. Long-latency responses evoked by vagal non-myelinated fibres were recorded in the medial subnucleus of the nucleus tractus solitarius, the area postrema, dorsal vagal motor nucleus, the parahypoglossal area and the lateral reticular formation dorsal to the nucleus ambiguus. A specific study was made of seventy-two single neurones activated by non-myelinated afferent fibres in the cardiac branch. Thirty-four were shown to be synaptically activated, twenty-one were activated nonsynaptically and seventeen could not be classified. One neurone was also activated by myelinated cardiac afferent fibres, and two by thoracic vagal (including pulmonary) afferent fibres. Neurones were not spontaneously active. Indirect evidence suggests that the majority of the recordings of nonsynaptically activated neurones were likely to be from cell bodies. Neurones were located from the level of the obex to 3.0 mm rostral to it in the medial subnucleus of the nucleus tractus solitarius (45), and in the lateral subnucleus (2), the area postrema and its border with the medial subnucleus of the nucleus tractus solitarius (13), the dorsal vagal motor nucleus (9), the parahypoglossal area (1) and the lateral reticular formation dorsal to nucleus ambiguus (2). Recordings were made from fifteen neurones activated by myelinated fibres in the cardiac vagal branches, and twelve were excited synaptically. The neurones were located in the medial (8) and lateral (3) subnuclei of the nucleus tractus solitarius, the dorsal vagal motor nucleus (1) and the lateral reticular formation (1). Four neurones were also excited by vagal afferent fibres in the thoracic vagal nerve immediately caudal to the caudal cardiac branch.
在麻醉猫中，电刺激右侧心迷走神经分支，并在脑干记录诱发的“慢波”和单个神经元活动。在孤束核的内侧和外侧亚核、最后区、迷走神经背核、外侧网状结构和疑核中记录到由有髓迷走传入纤维兴奋诱发的短潜伏期“慢波”和多神经元活动。由迷走无髓纤维诱发的长潜伏期反应在孤束核内侧亚核、最后区、迷走神经背核、舌下旁区以及疑核背侧的外侧网状结构中记录到。对72个由心脏分支中的无髓传入纤维激活的单个神经元进行了专门研究。结果显示，34个神经元是通过突触激活的，21个是通过非突触激活的，17个无法分类。1个神经元也被有髓心脏传入纤维激活，2个被胸段迷走神经（包括肺）传入纤维激活。神经元无自发活动。间接证据表明，大多数非突触激活神经元的记录可能来自细胞体。神经元位于孤束核内侧亚核中从闩平面到其吻侧3.0毫米的水平（45个），以及外侧亚核（2个）、最后区及其与孤束核内侧亚核的边界（13个）、迷走神经背核（9个）、舌下旁区（1个）和疑核背侧的外侧网状结构（2个）。对15个由心脏迷走神经分支中的有髓纤维激活的神经元进行了记录，其中12个通过突触兴奋。这些神经元位于孤束核的内侧（8个）和外侧（3个）亚核、迷走神经背核（1个）和外侧网状结构（1个）。4个神经元也被紧随心脏分支尾侧的胸段迷走神经中的迷走传入纤维兴奋。
