Grünberger W, Boschitsch E
Geburtshilfe Frauenheilkd. 1981 Nov;41(11):787-90. doi: 10.1055/s-2008-1036991.
22 adolescent and adult female patients - 15 to 37 years old - with the Congenital Adrenogenital Syndrome (AGS) were examined. In only 7 cases the disease was diagnosed immediately after birth. Among 16 patients, which had already undergone a reconstructive operation of the external genitalia, only 5 were satisfied with its cosmetic and functional results. 11 women could not do a sexual intercourse due to the malformed external genitalia. Menarche occurred spontaneously in only 10 cases under cortisone-therapy. At the time of investigation only 4 patients had regular menstrual-cycles. Adolescents suffering from AGS should be referred to a pediatric-gynecologist not later than puberty to assure an individual guidance relating to menstruation, surgical intervention, sexual-life and fertility.
对22名年龄在15至37岁之间患有先天性肾上腺生殖综合征（AGS）的青春期及成年女性患者进行了检查。仅7例在出生后立即被诊断出该病。在16例已经接受过外生殖器重建手术的患者中，只有5例对其外观和功能效果感到满意。11名女性因外生殖器畸形无法进行性交。在接受可的松治疗的情况下，只有10例自然出现月经初潮。在调查时，只有4例患者月经周期规律。患有AGS的青少年应在青春期前转诊至儿科妇科医生处，以确保在月经、手术干预、性生活和生育方面得到个性化指导。
