Held K R, Burck U, Koske-Westphal T
Geburtshilfe Frauenheilkd. 1981 Sep;41(9):619-21. doi: 10.1055/s-2008-1036954.
In 114 pregnant women the results of the GBN saliva test were compared with the results of sex determination by prenatal chromosomal analysis. GBN test results predicting boys corresponded in 40,7% of the cases with male karyotypes, whereas test results predicting girls corresponded in 56,5% with female karyotypes. Mean age of the women tested was 35,9 +/- 3,6 years. The test results in women aged 35 or younger did not show a better correlation with the chromosomal sexing than in older women (46,5% and 48,4%). Saliva tests performed in the 16th to 20th week of gestation corresponded to the same extent with the chromosomal sex of the fetuses as those performed in the 21st to 32nd week of gestation (48,5% and 46,2%). The mode of ascertainment of the pregnant women and other factors possibly influencing the results are discussed. It is concluded that the GBN saliva test is not suitable for prenatal sex prediction in women of the age group investigated.
在114名孕妇中，将GBN唾液检测结果与产前染色体分析的性别鉴定结果进行了比较。GBN检测预测为男孩的结果在40.7%的病例中与男性核型相符，而预测为女孩的结果在56.5%的病例中与女性核型相符。接受检测的女性平均年龄为35.9±3.6岁。35岁及以下女性的检测结果与染色体性别鉴定的相关性并不比年长女性更好（分别为46.5%和48.4%）。在妊娠第16至20周进行的唾液检测与在第21至32周进行的唾液检测与胎儿染色体性别的相符程度相同（分别为48.5%和46.2%）。讨论了孕妇的确定方式以及其他可能影响结果的因素。得出的结论是，GBN唾液检测不适用于所研究年龄组女性的产前性别预测。
