Adam D
Geburtshilfe Frauenheilkd. 1982 Sep;42(9):662-5. doi: 10.1055/s-2008-1036941.
A brief review of the special aspects concerning the use and selection of chemotherapeutic agents and antibiotics in bacterial infections occurring in gynaecology both specifically and generally. In case of severe bacterial infections such as sepsis it is recommended to combine two antibodies (e.g. beta-lactam antibiotics with aminoglycosides or several beta-lactam antibiotics together). Special attention is given to the particularly effective broad-spectrum penicillins and cephalosporins as well as to the aminoglycoside antibiotics etc. Individual well-tried antibiotics are briefly characterised in respect of their anti-bacterial efficacy (sensitivity and resistance), their field of application, and their dosage. In particular, the possibilities of the therapy of infections by anaerobic microorganisms and fungi are pointed out. In addition, a brief description is given of antibacterial chemotherapy of pneumonias of urinary tract infections and specifically gynaecological infections (such as adnexitis, endometritis, parametritis, pelveoperitonitis) under the aspects of rational antibiotic treatment. The article includes by pointing out the possibilities of prophylactic administration of antibiotics especially in surgical procedures in the sense of a perioperative short-term prophylaxis.
简要回顾在妇科细菌感染中使用和选择化疗药物及抗生素的特殊方面,包括具体情况和一般情况。对于严重细菌感染如败血症,建议联合使用两种抗生素(如β-内酰胺类抗生素与氨基糖苷类抗生素或几种β-内酰胺类抗生素联合使用)。特别关注特别有效的广谱青霉素和头孢菌素以及氨基糖苷类抗生素等。就其抗菌效力(敏感性和耐药性)、应用领域和剂量而言,对个别经过充分试验的抗生素进行了简要描述。特别指出了治疗厌氧微生物和真菌感染的可能性。此外,从合理抗生素治疗的角度,简要描述了肺炎、尿路感染以及具体妇科感染(如附件炎、子宫内膜炎、子宫旁组织炎、盆腔腹膜炎)的抗菌化疗。文章还指出了抗生素预防性给药的可能性,特别是在外科手术中进行围手术期短期预防的意义。