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[Estrogen and progesterone receptors in corpus uteri carcinoma and their clinical significance].

作者信息

Kleine W, Fuchs A, deGregorio G, Geyer H

出版信息

Geburtshilfe Frauenheilkd. 1982 Dec;42(12):884-7. doi: 10.1055/s-2008-1037179.

DOI:10.1055/s-2008-1037179
PMID:6925560
Abstract

In 49 carcinomas of the endometrium of varying clinical stages the estrogen and progesterone receptors were studied by charcoal absorption methods. The cases were studied between 1979 and 1981. 64% of the investigated cases were receptor positive, 35% were receptor negative. Estrogen receptors were detected in 61% and progesterone receptors in 49% of the cases. Both estrogen and progesterone receptors were detected in 45% of the cases. The receptor status was correlated with the clinical stage, the microscopic differentiation and the age of the patient. In 30 cases with a follow-up of more than 3 months it was attempted to determine the prognostic value of the steroid receptor status in endometrial carcinoma. The treatment possibilities with progestational agents and antiestrogens and with tamoxifen were discussed in view of the receptor status.

摘要

相似文献

1
[Estrogen and progesterone receptors in corpus uteri carcinoma and their clinical significance].
Geburtshilfe Frauenheilkd. 1982 Dec;42(12):884-7. doi: 10.1055/s-2008-1037179.
2
Cytoplasmic estrogen and progesterone receptors as prognostic parameters in primary endometrial carcinoma.
Obstet Gynecol. 1986 Apr;67(4):463-7.
3
[Endometrial cancer and steroid hormone receptors].
Ugeskr Laeger. 1990 Feb 26;152(9):593-7.
4
Correlation of estrogen and progesterone receptors with histologic differentiation in endometrial adenocarcinoma.子宫内膜腺癌中雌激素和孕激素受体与组织学分化的相关性
Am J Pathol. 1979 Jul;96(1):171-83.
5
Estrogen and progesterone receptors in uterine sarcomas.子宫肉瘤中的雌激素和孕激素受体
Obstet Gynecol. 1986 Nov;68(5):709-14.
6
The prognostic importance of steroid receptors in endometrial carcinoma.
Obstet Gynecol. 1988 Sep;72(3 Pt 1):388-93.
7
Study of estrogen receptor, progesterone receptor, and the estrogen-regulated Mr 24,000 protein in patients with carcinomas of the endometrium and cervix.子宫内膜癌和宫颈癌患者雌激素受体、孕激素受体及雌激素调节的24000 Mr蛋白的研究
Cancer Res. 1989 Aug 1;49(15):4298-304.
8
[Steroid hormone receptors in mammary carcinoma. Immunohistochemical detection and prognostic significance].[乳腺癌中的类固醇激素受体。免疫组织化学检测及预后意义]
Zentralbl Pathol. 1991;137(3):233-41.
9
Prediction of clinical outcome with estrogen and progestin receptor concentrations and their relationships to clinical and histopathological variables in endometrial cancer.雌激素和孕激素受体浓度对子宫内膜癌临床结局的预测及其与临床和组织病理学变量的关系
Cancer Res. 1986 Oct;46(10):5380-4.
10
Effects of tamoxifen on steroid hormone receptors and hormone concentration and the results of DNA analysis by flow cytometry in endometrial carcinoma.他莫昔芬对子宫内膜癌类固醇激素受体、激素浓度的影响及流式细胞术DNA分析结果
Gynecol Oncol. 1999 Mar;72(3):331-6. doi: 10.1006/gyno.1998.5281.

引用本文的文献

1
The predictive value of steroid hormone receptor analysis in breast, endometrial and ovarian cancer.类固醇激素受体分析在乳腺癌、子宫内膜癌和卵巢癌中的预测价值。
Med Oncol Tumor Pharmacother. 1986;3(3-4):197-210. doi: 10.1007/BF02934996.
2
[Progesterone receptors in endometrial cancer--a deciding prognostic factor].子宫内膜癌中的孕激素受体——一个决定性的预后因素
Arch Gynecol Obstet. 1989;245(1-4):583-5. doi: 10.1007/BF02417445.