Kilpatrick C J, Kaufman D V, Galbraith J E, King J O
Clin Exp Neurol. 1981;18:161-8.
Fourteen patients with benign intracranial hypertension who failed to respond to medical treatment, were treated with optic nerve decompression to prevent the sequelae of chronic unrelieved papilloedema. The mechanism by which optic nerve decompression protects the optic nerve is uncertain. These patients were reviewed to evaluate the efficacy of the procedure in the treatment of benign intracranial hypertension and to assess its mechanism of action. Preoperatively all patients had papilloedema, 11 patients had visual obscurations and 6 patients had evidence of visual failure. Postoperatively, visual obscurations and papilloedema resolved in all patients, and 5 of 6 patients had no further deterioration of visual function. Six patients had symptoms of raised intracranial pressure preoperatively and in 3 the symptoms resolved after surgery. Three patients had unilateral optic nerve decompression and papilloedema resolved in both eyes. In 1 patient intracranial pressure monitoring revealed raised pressure preoperatively with no significant change in the first 24 hours after surgery. We conclude that optic nerve decompression is effective in the treatment of benign intracranial hypertension, has its effect locally, and in some patients may lower the intracranial pressure.
14例对药物治疗无效的良性颅内高压患者接受了视神经减压术，以预防慢性未缓解的视乳头水肿的后遗症。视神经减压保护视神经的机制尚不清楚。对这些患者进行了复查，以评估该手术治疗良性颅内高压的疗效，并评估其作用机制。术前所有患者均有视乳头水肿，11例患者有视力模糊，6例患者有视力减退的证据。术后，所有患者的视力模糊和视乳头水肿均消失，6例患者中有5例视力功能未进一步恶化。6例患者术前有颅内压升高的症状，其中3例术后症状缓解。3例患者接受了单侧视神经减压，双眼视乳头水肿均消失。1例患者术前颅内压监测显示压力升高，术后24小时内无明显变化。我们得出结论，视神经减压术治疗良性颅内高压有效，具有局部作用，在一些患者中可能降低颅内压。
