Pampiglione S, Franco F, Canestri Trotti G
Parassitologia. 1982 Dec;24(2-3):155-65.
Two human cases of subcutaneous dirofilariasis are described in a 41 year-old woman and in a 14 year-old boy living in Venice Lido. In the first case, the development of a nodule at the left forearm had been preceded by generalized symptoms such as pruriginous urticarioid patches in various regions of the body, transitory swellings and 8% eosinophilia. From the nodule, an adult female of Dirofilaria repens was recovered with embryos visible in the uterus. In the second case, the parasite was localized in the scrotum, where it had caused an extensive oedema with the formation of a nodule having the size of a nut. An immature female specimen of D. repens was found. In both cases, the serological tests (Indirect Haemoagglutination and Bentonite Flocculation) gave significant titres specific for filariasis (1:256 and 1:20 in the first case, 1:128 and 1:5 in the second, respectively). A parasitological survey of blood samples from 145 stray dogs captured in the territory of the Venice municipality revealed the presence of D. repens in 8.3% of cases, D. immitis in 4.8% and Dipetalonema reconditum in 0.7%. This is the first time that the aetiological agent of human subcutaneous dirofilariasis was identified as D. repens in Italy.
本文描述了两例人体皮下恶丝虫病病例，患者分别是一名41岁女性和一名14岁男孩，他们居住在威尼斯丽都。第一例中，患者左前臂出现结节之前，曾出现全身症状，如身体各部位瘙痒性荨麻疹样斑块、短暂肿胀以及8%的嗜酸性粒细胞增多。从结节中取出了一条成年雌性匐行恶丝虫，子宫内可见胚胎。第二例中，寄生虫位于阴囊，导致广泛水肿，并形成一个核桃大小的结节。发现了一条未成熟的雌性匐行恶丝虫标本。两例病例的血清学检测（间接血凝试验和膨润土絮凝试验）均给出了针对丝虫病的显著滴度（第一例分别为1:256和1:20，第二例分别为1:128和1:5）。对在威尼斯市捕获的145只流浪狗的血液样本进行寄生虫学调查发现，8.3%的病例感染了匐行恶丝虫，4.8%感染了犬恶丝虫，0.7%感染了隐匿双瓣线虫。这是意大利首次将人体皮下恶丝虫病的病原体鉴定为匐行恶丝虫。
