人脑水质子的体内核磁共振成像及T1测量

In vivo NMR imaging and T1 measurements of water protons in the human brain.

作者信息

Hazlewood C F, Yamanashi W S, Rangel R A, Todd L E

出版信息

Magn Reson Imaging. 1982;1(1):3-10. doi: 10.1016/0730-725x(82)90267-3.

Abstract

Nuclear magnetic resonance (NMR) proton density images of the human brain have been made by the FONAR method. Spin-lattice relaxation times, T1, of water hydrogen protons have been determined at random positions within frontal and temporal regions of the human brain. The primary purpose of this ongoing research is to accumulate a large data base of normal T1 values for water protons in normal human brain tissue. Our experience to date includes 31 measurements on 18 volunteer subjects, and the mean value +/- standard deviation is 215 +/- 42 msec. In addition, two metastatic lesions of the brain were studied and found to have T1 values longer than those for normal brain tissue.

摘要

已通过FONAR方法获得了人类大脑的核磁共振（NMR）质子密度图像。已在人类大脑额叶和颞叶区域内的随机位置测定了水氢质子的自旋晶格弛豫时间T1。这项正在进行的研究的主要目的是积累正常人类脑组织中水质子正常T1值的大型数据库。我们目前的经验包括对18名志愿者受试者进行的31次测量，平均值±标准差为215±42毫秒。此外，对两个脑转移瘤进行了研究，发现其T1值比正常脑组织的T1值更长。