Le Magnen J, Devos M
Neurosci Biobehav Rev. 1980;4 Suppl 1:29-32. doi: 10.1016/0149-7634(80)90044-5.
Liver glycogen content was determined in free feeding rats sacrificed at the beginning of nocturnal meals or 60 min later. It was found that the glycogen content at the beginning of meals and 60 min later was highly correlated with the cumulative food intake since the beginning of the dark cycle, and therefore, increased from meal to meal. The comparison of these correlations between the cumulative food intake and the liver glycogen at the beginning of the meal and 60 min after ruled out the possibility that a constant decrement of glycogen might be involved in both meal onset and prandial periodicity of feeding. Rather the results are consistent with the view that the glycogen load during the night is a minute carbohydrate store which, like the fat store, is involved in the diurnal 12/12 hr feeding periodicity.
在夜间进食开始时或60分钟后处死自由进食的大鼠，测定其肝脏糖原含量。结果发现，进食开始时和60分钟后的糖原含量与自黑暗周期开始以来的累积食物摄入量高度相关，因此，每餐都会增加。对进食开始时和60分钟后累积食物摄入量与肝脏糖原之间的这些相关性进行比较，排除了糖原持续减少可能参与进食开始和进食的餐间周期性的可能性。相反，这些结果与以下观点一致，即夜间的糖原负荷是一种微量碳水化合物储存，与脂肪储存一样，参与了12/12小时的昼夜进食周期。
