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谢菲尔德市的复发性淋病:问题的规模、流行病学意义及复发者的个人特征

Repeated gonorrhea in Sheffield: the size of the problem, epidemiologic significance, and personal characteristics of repeaters.

作者信息

Kinghorn G R, Pryce D, Morton R S

出版信息

Sex Transm Dis. 1982 Oct-Dec;9(4):165-9.

PMID:6927781
Abstract

A retrospective study was made of patients in Sheffield who had had repeated gonorrhea infections during 1976-1979. Repeaters--defined as individuals with at least one gonococcal reinfection within 12 months of their index infection in any year--were a constant proportion of the absolute number of individuals infected in any calendar year. Thus, an average of 18.2% of individuals were repeaters who contributed 30.3% of the annual number of heterosexually acquired gonococcal infections. Repeaters of either sex were more likely to be young, unmarried, unemployed, and black; they more commonly had a history of preceding sexually transmitted infections, other sexually transmitted diseases accompanying their gonorrhea, and gonococcal isolates relatively resistant to penicillin. Discriminant analysis of their characteristics suggests that potential repeaters might be predicted. It is hypothesized that the local incidence of gonorrhea is directly proportional to the number of repeaters, and it is felt that control endeavors should be focused on potential repeaters if the incidence of this disease is to be reduced.

摘要

对1976年至1979年间在谢菲尔德反复感染淋病的患者进行了一项回顾性研究。复发病例定义为在任何一年中,在初次感染后12个月内至少有一次淋球菌再感染的个体,在任何一个日历年中,复发病例在感染个体总数中所占比例恒定。因此,平均有18.2%的个体为复发病例,他们占每年异性传播淋病感染病例数的30.3%。两性的复发病例更有可能是年轻人、未婚、失业和黑人;他们更常见的情况是有性传播感染史、淋病伴有其他性传播疾病,以及淋球菌分离株对青霉素相对耐药。对其特征进行判别分析表明,可以预测潜在的复发病例。据推测,淋病的局部发病率与复发病例数成正比,并且认为如果要降低这种疾病的发病率,控制措施应集中在潜在的复发病例上。

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