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复发性淋病:重要性及危险因素分析

Repeated gonorrhea: an analysis of importance and risk factors.

作者信息

Brooks G F, Darrow W W, Day J A

出版信息

J Infect Dis. 1978 Feb;137(2):161-9. doi: 10.1093/infdis/137.2.161.

Abstract

This study was designed to assess the epidemiological importance of repeated infections due to Neisseria gonorrhoeae and to analyze variables potentially associated with repeated gonorrhea. The retrospective analysis was of 7,347 patients seen during one year, and the prospective study was of a stratified randomly selected sample of 429 patients. The 492 retrospectively identified repeaters constituted 0.06% of the county population and 6.7% of the clinic population. The 492 repeaters had 21.6% of the cases of gonorrhea reported from the county and 29.4% of the cases reported from the clinic. The repeaters tended to be younger than those without repeated infection (P less than 0.001), male (62%), black (81.7%), and residents of areas of lower socioeconomic status than those who were not repeaters (P less than 0.001). Most repeaters (73.5%) had not graduated from high school. Repeaters did not have significantly greater numbers of sex partners (P greater than 0.05) or greater exposure to prostitutes or clients than those who did not have repeated infections and less frequently had sexual contact while symptomatic. Intensive follow-up of the small number of high-risk repeaters and their contacts could result in a major reduction in the number of reported cases of gonorrhea.

摘要

本研究旨在评估淋病奈瑟菌反复感染的流行病学重要性,并分析可能与反复淋病相关的变量。回顾性分析了一年内就诊的7347例患者,前瞻性研究则是对429例患者进行分层随机抽样。回顾性确定的492例反复感染者占该县人口的0.06%,占诊所人口的6.7%。这492例反复感染者占该县报告淋病病例的21.6%,占诊所报告病例的29.4%。反复感染者往往比未反复感染的人更年轻(P<0.001),男性(62%),黑人(81.7%),且社会经济地位低于未反复感染的人(P<0.001)。大多数反复感染者(73.5%)未高中毕业。反复感染者的性伴侣数量并不显著多于未反复感染的人(P>0.05),接触妓女或嫖客的情况也不比未反复感染的人多,且在有症状时进行性接触的频率较低。对少数高危反复感染者及其接触者进行强化随访可能会大幅减少淋病报告病例数。

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