Gallagher D M, Epker B N
J Oral Surg. 1980 Feb;38(2):117-20.
Prophylactic antibiotics are often administered during orthognathic surgery to prevent infection. A total of 140 consecutive patients who underwent "clean" intraoral maxillary and mandibular orthognathic surgery and received antibiotics in the preoperative period are reviewed with respect to postoperative infection. In four patients, infections developed, two of which were related to alloplastic implants. The microorganisms cultured from the infections were species not normally found in oral infections. One patient had an antibiotic-induced anaphylactic reaction. The theory and applicability of antibiotic prophylaxis for intraoral orthognathic surgery are discussed.
正颌外科手术期间常使用预防性抗生素以预防感染。本文回顾了140例连续接受“清洁”的口腔内上颌和下颌正颌手术且术前接受抗生素治疗的患者的术后感染情况。4例患者发生了感染，其中2例与异体植入物有关。从感染部位培养出的微生物是口腔感染中通常不会发现的菌种。1例患者发生了抗生素诱导的过敏反应。本文还讨论了口腔内正颌手术抗生素预防的理论及适用性。
