肝脏乙二醛酶I和乙二醛酶II的进一步研究。180肉瘤和L1210白血病荷瘤小鼠中的活性。
Further studies on liver glyoxalase I and glyoxalase II. Activity in mice bearing sarcoma 180 and L1210 leukemia.
作者信息
Winter R, Piskorska D, Jerzykowski T
出版信息
Neoplasma. 1978;25(4):465-70.
PMID:692805
Abstract
Determinations were made of glyoxalase I and glyoxalase II acitivity in the liver of mice (BDF1 and DBA2 strains) bearing sarcoma 180 and L1210 leukemia in ascites form. A progressive decrease in the both glyoxalase I and glyoxalase II activities to about 40--60% of that of the control groups was observed within the developing period 8--9 days. Test results are interpreted in the light of the postulated role of this enzyme system in cell division and in the tumor development process.
摘要
对患有腹水型肉瘤180和L1210白血病的小鼠（BDF1和DBA2品系）肝脏中的乙二醛酶I和乙二醛酶II活性进行了测定。在8 - 9天的发育期间内，观察到乙二醛酶I和乙二醛酶II的活性均逐渐下降至对照组的约40 - 60%。根据该酶系统在细胞分裂和肿瘤发展过程中假定的作用对测试结果进行了解释。
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