Worsaae N, Pindborg J J
Oral Surg Oral Med Oral Pathol. 1980 Feb;49(2):131-8. doi: 10.1016/0030-4220(80)90305-9.
Of thirty patients with complete or incomplete forms of Melkersson-Rosenthal syndrome, five patients with gingival lesions that microscopically showed the characteristic granulomatous changes are presented, with special reference to their gingival manifestations. In some cases bluish red, small, distinct, and irregular edematous swellings characterized the gingival changes, while in other cases more extensive and diffuse, edematous swellings dominated. All five patients had only vague symptoms from the gingiva. Because of the apparent slowly progressing nature of the gingival swellings and occasional spontaneous regression of the gingival changes, a conservative attitude in the treatment of gingival lesions in MRS is recommended. Gingival symptoms may be the first manifestation of the disease, and it is emphasized that, with an increased diagnostic awareness, gingival involvement may be found more commonly in patients with MRS.
在30例患有完全型或不完全型梅尔克森－罗森塔尔综合征的患者中，本文报告了5例有牙龈病变的患者，这些病变在显微镜下显示出特征性的肉芽肿性改变，并特别提及了他们的牙龈表现。在某些病例中，牙龈变化表现为蓝红色、小而清晰且不规则的水肿性肿胀，而在其他病例中则以更广泛、弥漫的水肿性肿胀为主。所有5例患者牙龈仅有模糊症状。由于牙龈肿胀明显呈缓慢进展性且牙龈变化偶尔会自发消退，因此建议对梅尔克森－罗森塔尔综合征的牙龈病变采取保守治疗态度。牙龈症状可能是该病的首发表现，并且需要强调的是，随着诊断意识的提高，梅尔克森－罗森塔尔综合征患者中牙龈受累可能更常见。
