Colbert N, Najman A, Gorin N C, Blum F, Treisser A, Lasfargues G, Cloup M, Barrat H, Duhamel G
Nouv Presse Med. 1980 Jan 12;9(3):175-8.
A report of two cases of acute leukaemia discovered during pregnancy. The first was treated from the 24th week with cytosine arabinoside, daunorubicine and vincristine and then rubidazone. Only an incomplete remission was obtained. The pregnancy ended with the birth at the 36th week of a normal child, which remains well at the age of 13 months. The second patient received during the 29th week of pregnancy chemotherapy combining cytosine arabinoside and daunorubicine. Signs of foetal distress appeared at 31 weeks. Delivery took place during the 33rd week in a phase of aplasia. The child was born apparently dead and was resuscitated. A complete remission of the leukaemia was obtained. The child was well at the age of 13 months. A transient neutropaenia was noted at the age of 2 months in both children.
两例孕期发现急性白血病的病例报告。第一例从第24周开始用阿糖胞苷、柔红霉素和长春新碱治疗，随后用鲁比唑。仅获得不完全缓解。妊娠在第36周时以一名正常婴儿出生结束，该婴儿在13个月大时情况良好。第二例患者在妊娠第29周接受了阿糖胞苷和柔红霉素联合化疗。31周时出现胎儿窘迫迹象。在第33周再生障碍期进行了分娩。孩子出生时明显死亡，后经复苏。白血病获得完全缓解。孩子在13个月大时情况良好。两个孩子在2个月大时均出现短暂性中性粒细胞减少。
