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电外科治疗苯妥英钠所致牙龈增生

Treatment of phenytoin-induced gingival hyperplasia by electrosurgery.

作者信息

Walker C R, Tomich C E, Hutton C E

出版信息

J Oral Surg. 1980 Apr;38(4):306-11.

PMID:6928462
Abstract

Many medications and combinations of medications are available for the control of epilepsy, but phenytoin continues to be the most effective agent for most patients. A common side effect of this drug is the development of moderate to severe gingival hyperplasia in tooth-bearing areas, which can contribute to problems of function, oral hygiene, appearance, and, eventually, loss of teeth. Excision by conventional means is technically difficult, time-consuming, may be associated with considerable loss of blood, and requires postoperative care, such as periodontal packing, that is impractical if not impossible for many patients, especially the severely mentally handicapped. We have described a technique of gingivectomy using an electrosurgical device in the hospital with the patient under general anesthesia that has produced good results for more than 15 years. This procedure has virtually eliminated the problems of conventional surgical excision with little or no postoperative sequelae.

摘要

有许多药物及药物组合可用于控制癫痫,但对大多数患者来说苯妥英仍然是最有效的药物。该药的一个常见副作用是在有牙区出现中度至重度牙龈增生,这可能会导致功能、口腔卫生、外观等问题,最终还会导致牙齿脱落。采用传统方法切除在技术上难度大、耗时,可能会导致大量出血,并且需要术后护理,如牙周填塞,这对许多患者来说即便并非不可能也是不切实际的,尤其是对重度智力障碍患者。我们已经描述了一种在医院全身麻醉下使用电外科设备进行牙龈切除术的技术,该技术15多年来一直产生良好效果。此手术几乎消除了传统手术切除的问题,术后后遗症很少或没有。

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