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与唇腭裂及唇瘘相关的口腔粘连。

Oral adhesions associated with cleft lip and palate and lip fistulae.

作者信息

Shaw W C, Simpson J P

出版信息

Cleft Palate J. 1980 Apr;17(2):127-31.

PMID:6929230
Abstract

Three cases of congenital strand-like adhesions between the upper and lower gum pads associated with cleft lip and palate and lower lip fistulae are reported. A consideration of the literature would suggest that this may represent an autosomal dominant trait with variable penetrance and expressivity though a positive family history was found in only one case. The adhesions may have arisen by persistence of the oropharyngeal membrane or anomalous fusion of adjacent epithelial surfaces, the latter seeming rather more likely in the present series. The clinical implications are discussed.

摘要

报告了3例上、下牙龈垫之间存在先天性条索状粘连,伴有唇腭裂和下唇瘘的病例。查阅文献后发现,尽管仅在1例中发现了阳性家族史,但这可能代表一种具有可变外显率和表现度的常染色体显性性状。粘连可能是由于口咽膜持续存在或相邻上皮表面异常融合所致,在本系列病例中,后者似乎更有可能。文中讨论了其临床意义。

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