Ademiluyi S A, Oyeneyin J O, Sowemimo G O
West Afr J Med. 1989 Apr-Jun;8(2):135-8.
This is a prospective study of 106 patients with cleft lip and or palate seen over a 5 year period between January 1981 and December, 1985 at the Lagos University Teaching Hospital. Thirty of these patients (28.3 percent) have other associated congenital anomalies which lies within the range of 3 percent to 63.3 percent reported by other authors. The associated anomaly rate was 19 percent in cleft lip only, 35 percent in cleft lip and palate and 28 percent in cleft palate only. All the associated anomalies in the cleft lip cases were single and simple. On the other hand, the multiple and more complex associated anomalies occurred in patients with cleft plate alone and cleft lip and palate combined. Three syndromes were recognised in patients with cleft palate and two in patients with cleft lip and palate.
这是一项前瞻性研究,研究对象为1981年1月至1985年12月这5年期间在拉各斯大学教学医院就诊的106例唇腭裂患者。其中30例患者(28.3%)伴有其他先天性异常,这一比例在其他作者报告的3%至63.3%范围内。单纯唇裂患者的相关异常率为19%,唇腭裂患者为35%,单纯腭裂患者为28%。唇裂病例中的所有相关异常均为单一且简单的。另一方面,多种且更复杂的相关异常发生在单纯腭裂患者以及唇腭裂合并患者中。腭裂患者中识别出三种综合征,唇腭裂患者中识别出两种综合征。