Brumback R A
Aust N Z J Med. 1980 Apr;10(2):224-6. doi: 10.1111/j.1445-5994.1980.tb03718.x.
A case of acute inflammatory polyradioculoneuropathy (IPN, Guillain-Barré syndrome) not responding to oral corticosteroids but showing marked improvement on parenteral corticosteroids is reported. Oral prednisone 60 mg/day was begun on hospital admission and increased after one week to 100 mg/day; however, the patient's respiratory function, demonstrated by forced vital capacity, continued to deteriorate. Improvement was noted when the patient was switched to intravenous methyl-prednisolone 100 mg/day. Further attempts to use oral corticosteroids (including oral methyl-prednisolone 96 mg/day) resulted in deterioration of the patient's function.
报告了一例急性炎症性多神经根神经病（IPN，吉兰 - 巴雷综合征），口服皮质类固醇无效，但肠外给予皮质类固醇后有显著改善。入院时开始口服泼尼松60毫克/天，一周后增至100毫克/天；然而，通过用力肺活量测定的患者呼吸功能持续恶化。当患者改用静脉注射甲泼尼龙100毫克/天时，情况有所改善。进一步尝试使用口服皮质类固醇（包括口服甲泼尼龙96毫克/天）导致患者功能恶化。
