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Three-dimensional structure of a pyridoxal-phosphate-dependent enzyme, mitochondrial aspartate aminotransferase.一种磷酸吡哆醛依赖性酶——线粒体天冬氨酸氨基转移酶的三维结构
Proc Natl Acad Sci U S A. 1980 May;77(5):2559-63. doi: 10.1073/pnas.77.5.2559.
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Three-dimensional structure of mitochondrial aspartate aminotransferase and some functional derivatives: implications for its mode of action.
Biochem Soc Trans. 1984 Jun;12(3):424-7. doi: 10.1042/bst0120424.
3
Mutant aspartate aminotransferase (K258H) without pyridoxal-5'-phosphate-binding lysine residue. Structural and catalytic properties.不含磷酸吡哆醛结合赖氨酸残基的突变天冬氨酸转氨酶（K258H）。结构和催化特性。
Eur J Biochem. 1993 Feb 1;211(3):475-84. doi: 10.1111/j.1432-1033.1993.tb17573.x.
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Linear dichroism measurements on single crystals of mitochondrial aspartate aminotransferase.
Prog Clin Biol Res. 1984;144B:233-43.
5
Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase.
Eur J Biochem. 1996 Mar 15;236(3):1025-32. doi: 10.1111/j.1432-1033.1996.01025.x.
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Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase.酿酒酵母胞质天冬氨酸转氨酶的晶体结构
Protein Sci. 1998 Jun;7(6):1380-7. doi: 10.1002/pro.5560070614.
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X-ray structure refinement and comparison of three forms of mitochondrial aspartate aminotransferase.
J Mol Biol. 1992 May 20;225(2):495-517. doi: 10.1016/0022-2836(92)90935-d.
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Changing the reaction specificity of a pyridoxal-5'-phosphate-dependent enzyme.改变磷酸吡哆醛依赖性酶的反应特异性。
Eur J Biochem. 1995 Sep 1;232(2):686-90. doi: 10.1111/j.1432-1033.1995.tb20861.x.
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Crystallographic studies on the mechanism of action of mitochondrial aspartate aminotransferase.
Prog Clin Biol Res. 1984;144B:195-203.
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Reorientations of coenzyme in the active site of chicken cytosolic aspartate aminotransferase.鸡胞质天冬氨酸转氨酶活性位点中辅酶的重新定向
Prog Clin Biol Res. 1984;144B:213-21.
引用本文的文献
1
Aspartate aminotransferase of has extended substrate specificity and metabolizes aspartate to enable N fixation in pea nodules.具有扩展的底物特异性的天冬氨酸氨基转移酶可代谢天冬氨酸以实现豌豆根瘤中的固氮作用。
Microbiology (Reading). 2024 Jul;170(7). doi: 10.1099/mic.0.001471.
2
Cysteine Aminotransferase (CAT): A Pivotal Sponsor in Metabolic Remodeling and an Ally of 3-Mercaptopyruvate Sulfurtransferase (MST) in Cancer.半胱氨酸氨基转移酶（CAT）：代谢重塑的关键调控因子，也是 3-巯基丙酮酸硫转移酶（MST）在癌症中的盟友。
Molecules. 2020 Sep 1;25(17):3984. doi: 10.3390/molecules25173984.
3
Crystal structure of L-aspartate aminotransferase from Schizosaccharomyces pombe.酿酒酵母天冬氨酸氨基转移酶的晶体结构。
PLoS One. 2019 Aug 29;14(8):e0221975. doi: 10.1371/journal.pone.0221975. eCollection 2019.
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Computational classification of MocR transcriptional regulators into subgroups as a support for experimental and functional characterization.将MocR转录调节因子计算分类为亚组，以支持实验和功能表征。
Bioinformation. 2019 Feb 28;15(2):151-159. doi: 10.6026/97320630015151. eCollection 2019.
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The Synthesis of Kynurenic Acid in Mammals: An Updated Kynurenine Aminotransferase Structural KATalogue.哺乳动物中犬尿喹啉酸的合成：犬尿氨酸转氨酶结构目录的更新
Front Mol Biosci. 2019 Feb 27;6:7. doi: 10.3389/fmolb.2019.00007. eCollection 2019.
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Immunological measurement of aspartate/alanine aminotransferase in predicting liver fibrosis and inflammation.天门冬氨酸/丙氨酸氨基转移酶的免疫学测定在预测肝纤维化和炎症中的作用。
Korean J Intern Med. 2020 Mar;35(2):320-330. doi: 10.3904/kjim.2018.214. Epub 2019 Jan 23.
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The Effect of Vitamin E and Metallothionein on the Antioxidant Capacities of Cadmium-Damaged Liver in Grass Carp .维生素 E 和金属硫蛋白对镉损伤草鱼肝脏抗氧化能力的影响。
Biomed Res Int. 2018 Nov 4;2018:7935396. doi: 10.1155/2018/7935396. eCollection 2018.
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Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia.布氏锥虫、硕大利什曼原虫和蓝氏贾第鞭毛虫中天冬氨酸转氨酶的结构。
Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):566-71. doi: 10.1107/S2053230X15001831. Epub 2015 Apr 21.
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Overexpression, purification, crystallization and structure determination of AspB, a putative aspartate aminotransferase from Mycobacterium tuberculosis.来自结核分枝杆菌的一种假定天冬氨酸转氨酶AspB的过表达、纯化、结晶及结构测定
Acta Crystallogr F Struct Biol Commun. 2014 Jul;70(Pt 7):928-32. doi: 10.1107/S2053230X14011820. Epub 2014 Jun 18.
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Aspartate aminotransferases ofPanicum miliaceum L. andPanicum antidotale retz. : Inactivation and reconstitution.黑麦和狗尾草天冬氨酸转氨酶：失活与复性。
Planta. 1982 Sep;154(5):477-84. doi: 10.1007/BF01267817.
本文引用的文献
1
The site of binding of pyridoxal-5'-phosphate to heart glutamic-aspartic transaminase.磷酸吡哆醛与心脏谷草转氨酶的结合位点。
Proc Natl Acad Sci U S A. 1962 Sep 15;48(9):1615-8. doi: 10.1073/pnas.48.9.1615.
2
The complete amino acid sequence of cytoplasmic aspartate aminotransferase from pig heart.猪心脏胞质天冬氨酸转氨酶的完整氨基酸序列。
FEBS Lett. 1973 Jan 1;29(1):31-34. doi: 10.1016/0014-5793(73)80008-0.
3
Identification of the functionally important cysteinyl residue in pig heart aspartate aminotransferase.
FEBS Lett. 1972 Dec 15;28(3):302-304. doi: 10.1016/0014-5793(72)80736-1.
4
Evidence of a critical histidine residue in soluble aspartic aminotransferase.可溶性天冬氨酸转氨酶中关键组氨酸残基的证据。
J Biol Chem. 1967 Apr 10;242(7):1426-30.
5
The matching of physical models to three-dimensional electron-density maps: a simple optical device.物理模型与三维电子密度图的匹配：一种简单的光学装置。
J Mol Biol. 1968 Oct 14;37(1):225-30. doi: 10.1016/0022-2836(68)90085-5.
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The mechanism of transamination. Function of the histidyl residue at the active site of supernatant aspartate transaminase.转氨基作用的机制。上清液天冬氨酸转氨酶活性位点处组氨酰残基的功能。
J Biol Chem. 1970 Feb 25;245(4):806-13.
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The effect of tetranitromethane on apo-aspartate-aminotransferase from pig heart.
Eur J Biochem. 1971 Nov 11;23(2):349-54. doi: 10.1111/j.1432-1033.1971.tb01628.x.
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The structure of thermolysin: an electron density map at 2-3 A resolution.嗜热菌蛋白酶的结构：分辨率为2 - 3埃的电子密度图。
J Mol Biol. 1972 Oct 14;70(3):701-24. doi: 10.1016/0022-2836(72)90569-4.
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Stereochemical aspects of pyridoxal phosphate catalysis.磷酸吡哆醛催化作用的立体化学方面
Adv Enzymol Relat Areas Mol Biol. 1971;35:79-134. doi: 10.1002/9780470122808.ch3.
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Dynamic three-dimensional model for enzymic transamination.
Adv Enzymol Relat Areas Mol Biol. 1969;32:21-53. doi: 10.1002/9780470122778.ch2.
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