Bowen J H, Woodward B H, Mossler J A, Ingram P, Shelburne J D
Arch Pathol Lab Med. 1980 Sep;104(9):459-61.
Since the recognition of the development of certain malignant neoplasms in association with thorium dioxide (Thorotrast), its presence has been documented by light microscopic appearance and time-consuming autoradiography. Energy dispersive x-ray microanalysis can be used in the rapid documentation of thorium in paraffin-embedded tissues and it is confirmed that thorium is the principal component of the granular deposits described by light microscopy.
