Friedman J, McCallum P, Meares R
Aust N Z J Psychiatry. 1980 Jun;14(2):115-9. doi: 10.3109/00048678009159365.
The perceived intensity of a stimulus may be magnified during depression. Stimulus intensity control can be studied by means of cortical evoked potentials. In a study of 33 depressives, cortical evoked potentials were greater during depression than on recovery. The effect of doxepin on the amplitudes of evoked potentials of depressives was compared with that of amitriptyline. Doxepin reduced amplitudes. Amitriptyline had a similar, but non-significant effect.
在抑郁期间,刺激的感知强度可能会被放大。刺激强度控制可以通过皮层诱发电位来研究。在一项对33名抑郁症患者的研究中,抑郁期间的皮层诱发电位比康复时更大。将多塞平对抑郁症患者诱发电位振幅的影响与阿米替林的影响进行了比较。多塞平降低了振幅。阿米替林有类似但不显著的效果。