Perlow M J, Kumakura K, Guidotti A
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5278-81. doi: 10.1073/pnas.77.9.5278.
Dispersed, cultured bovine adrenal chromaffin cells transplanted into the cerebral ventricles of neonatal and adult rats survived at least 2 mo without evidence of immunological rejection. The cells can be identified by their strong yellow fluorescent reaction with glyoxylic acid, which suggests that they maintain intact the capability of synthesizing and storing catecholamines. The cells did not show sprouting or process formation and appeared to be free in the ventricle or aggregated in clusters. This shows that cells from different animal species and from different tissue origins can be transplanted and can survive in the cerebral ventricles.
分散培养的牛肾上腺嗜铬细胞移植到新生大鼠和成年大鼠的脑室中，至少存活了2个月，没有免疫排斥的迹象。这些细胞可以通过与乙醛酸的强烈黄色荧光反应来识别，这表明它们保持了合成和储存儿茶酚胺的完整能力。这些细胞没有显示出发芽或形成突起，似乎在脑室中是游离的或聚集成簇。这表明来自不同动物物种和不同组织来源的细胞可以被移植并在脑室中存活。
