Kahn P, Aldor E
Wien Klin Wochenschr. 1980 Aug 1;92(15):538-40.
The serum myoglobin level was determined in 45 healthy persons and 64 patients of whom 43 had a recent proven myocardial infarct. The normal myoglobin value was found to ae 43.7 +/- 16.0 ng/ml. All the patients with myocardial infarct who had been transferred to our Coronary Care Unit showed raised serum myoglobin levels already 4 hours after symptoms commenced, the maximum being reached after 10 hours. 20 hours after myocardial infarction normal values were once again registered. Pathological serum myoglobin levels were also found without infarction after skeletal muscle damage in the course of resuscitation measures, or after operations or in renal failure. The value of the serum myoglobin concentration in the diagnosis of myocardial infarction lies in the early elevation of this parameter, but it is unspecific and the method is relatively laborious.
对45名健康人和64名患者测定了血清肌红蛋白水平，其中43名患者近期经证实发生心肌梗死。正常肌红蛋白值为43.7±16.0纳克/毫升。所有转入我们冠心病监护病房的心肌梗死患者在症状出现后4小时血清肌红蛋白水平就已升高，10小时后达到最高值。心肌梗死后20小时再次出现正常值。在复苏措施过程中骨骼肌损伤后、手术后或肾衰竭时，未发生梗死也可发现病理性血清肌红蛋白水平。血清肌红蛋白浓度在心肌梗死诊断中的价值在于该参数的早期升高，但它不具有特异性且该方法相对繁琐。
