Sulman F G
Ups J Med Sci Suppl. 1980;31:41-4.
Attacks of migraine resulting from climatic cold or heat-stress are a common occurrence in 20-30 per cent of a population exposed to weather changes. The electrical charges (positive ionisation and sferics) engendered by every incoming weather front produce a release of serotonin. In addition there also exists a syndrome of adrenaline deficiency, which may produce headache, while a third reaction, intermittent hyperthyreosis, plays a lesser role in evoking headache. The differential diagnosis of the various types of headache is based upon the profile of neurohormones excreted in the 24-hours urinary output, which permits a comparison between normal and weather-stress days. Such a procedure may provide an appraisal of the underlying metabolic disturbance. Consequently, appropriate treatment can be administered to the patient, and its effect controlled by analysis of any possible neurohormonal change.
在暴露于天气变化的人群中，20%至30%的人会因气候寒冷或热应激而出现偏头痛发作。每次天气锋面到来所产生的电荷（正电离和天电）会导致血清素释放。此外，还存在肾上腺素缺乏综合征，这可能会引发头痛，而第三种反应，即间歇性甲状腺功能亢进，在引发头痛方面作用较小。各种类型头痛的鉴别诊断基于24小时尿量中排出的神经激素谱，这使得能够比较正常天气和天气应激日的情况。这样的程序可以对潜在的代谢紊乱进行评估。因此，可以对患者进行适当的治疗，并通过分析任何可能的神经激素变化来控制其效果。
