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过敏性疾病的特异性免疫疗法:应用、效果及副作用(作者译)

[Specific immunotherapy of allergic diseases: application, effect and side-effects (author's transl)].

作者信息

Jarisch R, Sandor I, Götz M, Popow C

出版信息

Wien Klin Wochenschr Suppl. 1980;117:15-8.

PMID:6936976
Abstract

Based on the results of 500 patients suffering from bee-venom allergy, allergic rhinitis, bronchial asthma, atopic dermatitis and food allergy the necessary diagnostic procedures leading to specific immunotherapy are discussed. The immunstimulating potential of the vaccines varies from patient to patient and is decreased after some viral infections. Good results are seen in young patients and when a low number of allergens is incorporated in the vaccine. Side effects of minor importance are seen in about half the patients. Systemic reactions following specific immunotherapy are seen more often in aqueous solutions compared to depot vaccines. The treatment should be reconsidered, if the patient has not improved after half a year.

摘要

基于500例蜂毒过敏、过敏性鼻炎、支气管哮喘、特应性皮炎和食物过敏患者的结果,讨论了导致特异性免疫疗法的必要诊断程序。疫苗的免疫刺激潜力因患者而异,在一些病毒感染后会降低。年轻患者以及疫苗中过敏原数量较少时效果较好。约一半患者会出现不太严重的副作用。与长效疫苗相比,特异性免疫疗法后的全身反应在水溶液中更常见。如果患者半年后没有改善,应重新考虑治疗方案。

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