Joyce J G, Lenaghan D
Aust N Z J Surg. 1980 Dec;50(6):603-9. doi: 10.1111/j.1445-2197.1980.tb04206.x.
The results obtained in 37 patients treated by partial cystectomy and 51 patients treated by total cystectomy are presented. Partial cystectomy was usually performed for deeply invasive tumours. THere were no operative deaths, but 85% of the patients died in the first two years of follow-up and the five-year survival was 11%. Of the 51 patients having total cystectomy, 22 were operated upon after other treatments had failed. There were six (11.8%) operative deaths, only one following simple cystectomy, and the remainder following radical cystectomy with or without urethrectomy. Almost half the survivors died in the first two years, and the five-year survival was 31%. The better prognosis in total cystectomy is attributable to the presence of a number of patients with multicentric but relatively non-invasive tumours. Thirteen patients, all with invasive bladder tumours, had 4,000 R irradiation to the pelvis before operation. There was no benefit demonstrated in this combined treatment. The loss survival rate despite treatment in deeply invasive bladder tumours indicates the value of early diagnosis and the need for more effective forms of treatment.
本文展示了37例行部分膀胱切除术和51例行全膀胱切除术患者的治疗结果。部分膀胱切除术通常用于治疗浸润性较深的肿瘤。手术无死亡病例，但85%的患者在随访的头两年内死亡，五年生存率为11%。在51例行全膀胱切除术的患者中，22例是在其他治疗失败后接受手术的。有6例（11.8%）手术死亡，仅1例死于单纯膀胱切除术，其余死于根治性膀胱切除术（伴或不伴尿道切除术）。几乎一半的幸存者在头两年内死亡，五年生存率为31%。全膀胱切除术预后较好归因于有一些多中心但相对非浸润性肿瘤的患者。13例均为浸润性膀胱肿瘤患者，术前接受了盆腔4000伦琴的放疗。这种联合治疗未显示出益处。浸润性膀胱肿瘤尽管接受了治疗但生存率仍低，这表明早期诊断的价值以及需要更有效的治疗方式。
