Vogel R I
J Periodontol. 1981 Jan;52(1):20-3. doi: 10.1902/jop.1981.52.1.20.
Inflammatory periodontal disease arises as a response to bacterial plaque. This response, however, may be modified by systemic factors such as nutritional deficiency, hormonal imbalance or severe systemic disease. One such systemic disease that may modify host response to local etiologic factors is systemic lupus erythematosus (SLE). Depression of thrombocyte production is very rarely associated with SLE. A search of the medical literature has revealed only one such reported case. The case history that follows is of a 17-year-old black female with severe gingivitis and spontaneous gingival bleeding associated with systemic lupus erythematosus and amegakaryocytic thrombocytopenia. It is believed to be the first such case reported in the dental literature. The clinical, radiographic and hematologic findings will be presented and the medical and periodontal therapy discussed.
炎症性牙周病是对细菌菌斑的一种反应。然而，这种反应可能会受到全身因素的影响，如营养缺乏、激素失衡或严重的全身性疾病。系统性红斑狼疮（SLE）就是一种可能改变宿主对局部致病因素反应的全身性疾病。血小板生成减少很少与SLE相关。检索医学文献仅发现一例此类报道病例。以下病例报告是一名17岁黑人女性，患有严重牙龈炎和自发性牙龈出血，伴有系统性红斑狼疮和无巨核细胞性血小板减少症。据信这是牙科文献中首例此类病例报告。将展示临床、影像学和血液学检查结果，并讨论医学和牙周治疗方法。
