Michelson A M, Puget K
Acta Physiol Scand Suppl. 1980;492:67-80.
The fixation and penetration of liposomal encapsulated dismutase (SOD) with human erythrocytes and other eucaryote cells is described. Such preparations not only facilitate fixation and penetration of the enzyme as a function of liposome composition, but also confer an increased physiological life time as well as a marked organ specificity. Such packed SOD could be useful for a pharmacological application of the enzyme.
描述了脂质体包裹的超氧化物歧化酶(SOD)与人红细胞及其他真核细胞的固定和渗透情况。这类制剂不仅根据脂质体组成促进酶的固定和渗透,还能延长其生理寿命并赋予显著的器官特异性。这种包装的超氧化物歧化酶对于该酶的药理学应用可能有用。