“微颗粒型”急性早幼粒细胞白血病（FAB M3m）的形态学与细胞化学

Morphology and cytochemistry of "microgranular" acute promyelocytic leukemia (FAB M3m).

作者信息

Savage R A, Hoffman G C, Lucas F V

出版信息

Am J Clin Pathol. 1981 Apr;75(4):548-52. doi: 10.1093/ajcp/75.4.548.

DOI:10.1093/ajcp/75.4.548

Abstract

Three cases of a newly recognized "microgranular" variant of acute promyelocytic leukemia (FAB M3) are described. This poor-prognosis variant is easily confused with myelomonocytic (M4) or monocytic (M5) leukemia, but is associated with disseminated intravascular coagulation as is "hypergranular" M3. Such patients may be inappropriately treated unless the promyelocytic nature of the leukemia is recognized.

摘要

本文描述了3例新发现的急性早幼粒细胞白血病（FAB M3）“微颗粒”变异型病例。这种预后不良的变异型易与粒单核细胞白血病（M4）或单核细胞白血病（M5）相混淆，但与“粗颗粒”M3一样，与弥散性血管内凝血有关。除非认识到白血病的早幼粒细胞性质，否则这类患者可能会接受不恰当的治疗。