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犬血酸碱曲线列线图

Acid-base curve nomogram for dog blood.

作者信息

Emuakpor D S, Maas A H, Ruigrok T J, Zimmerman A N

出版信息

Pflugers Arch. 1976 May 12;363(2):141-7. doi: 10.1007/BF01062282.

DOI:10.1007/BF01062282
PMID:6940
Abstract

Pooled canine blood of different hemoglobin concentration was equilibrated with two carbon dioxide tensions and the resulting pH's of the samples were measured at 38 degrees C. Readings obtained provided data for the construction of a cartesian nomogram for the dog, based on the pH/log pCO2 coordinate system. The nomogram can be used to evaluate both respiratory and non-respiratory acid-base parameters. For contrast, a control nomogram on human blood was also constructed. Both nomograms show broad similarity. This is to be expected as the normal criteria used to define base excess relating to dog blood are the same as those used for human blood. Nonetheless, base excess and buffer base calculations using the nomogram for the dog and that for man show a deviation of 2.5-10%, and we consider this deviation to be more due to a species difference than to any summated experimental error.

摘要

将不同血红蛋白浓度的犬类混合血液与两种二氧化碳分压进行平衡,并在38摄氏度下测量样品的最终pH值。所获得的读数为基于pH/对数pCO₂坐标系构建犬类笛卡尔列线图提供了数据。该列线图可用于评估呼吸和非呼吸酸碱参数。作为对比,还构建了人类血液的对照列线图。两种列线图显示出广泛的相似性。这是可以预料的,因为用于定义与犬类血液相关的碱剩余的正常标准与用于人类血液的标准相同。尽管如此,使用犬类列线图和人类列线图进行的碱剩余和缓冲碱计算显示偏差为2.5 - 10%,我们认为这种偏差更多是由于物种差异而非任何累积的实验误差。

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本文引用的文献

1
An improved clinical method for the estimation of disturbances of the acid-base balance of human blood.一种用于评估人体血液酸碱平衡紊乱的改良临床方法。
Medicine (Baltimore). 1948 May;27(2):223-242. doi: 10.1097/00005792-194805000-00003.
2
Determination of serum proteins by means of the biuret reaction.通过双缩脲反应测定血清蛋白。
J Biol Chem. 1949 Feb;177(2):751-66.
3
Standardization of hemoglobinometry. II. The hemiglobincyanide method.血红蛋白测定法的标准化。II. 高铁氰化血红蛋白法。
Clin Chim Acta. 1961 Jul;6:538-44. doi: 10.1016/0009-8981(61)90145-0.
4
The pH-log pCO2 blood acid-base nomogram revised.修订后的pH-log pCO₂血液酸碱列线图。
Scand J Clin Lab Invest. 1962;14:598-604. doi: 10.1080/00365516209051290.
5
Blood acid-base alignment nomogram. Scales for pH, pCO2 base excess of whole blood of different hemoglobin concentrations, plasma bicarbonate, and plasma total-CO2.血液酸碱平衡列线图。不同血红蛋白浓度全血的pH、pCO₂、碱剩余、血浆碳酸氢盐及血浆总二氧化碳的刻度。
Scand J Clin Lab Invest. 1963;15:211-7. doi: 10.3109/00365516309079734.
6
The acid-base status of the blood.血液的酸碱状态。
Scand J Clin Lab Invest. 1963;15 Suppl 70:1-134.
7
A new acid-base nomogram. An improved method for the calculation of the relevant blood acid-base data.一种新的酸碱列线图。一种计算相关血液酸碱数据的改进方法。
Scand J Clin Lab Invest. 1960;12:177-86. doi: 10.3109/00365516009062420.
8
Standard bicarbonate, its clinical significance, and a new method for its determination.标准碳酸氢盐、其临床意义及一种新的测定方法。
Scand J Clin Lab Invest. 1957;9(2):122-32. doi: 10.3109/00365515709101210.
9
A computer program for the blood pH-log pCO2 nomogram.用于血液pH值-对数二氧化碳分压列线图的计算机程序。
Scand J Clin Lab Invest. 1967;19(1):29-37. doi: 10.3109/00365516709093478.
10
Blood gas calculator.血气计算器。
J Appl Physiol. 1966 May;21(3):1108-16. doi: 10.1152/jappl.1966.21.3.1108.